Stephanie, D.J. and Kimmy go out that night, leaving Jesse in charge of watching Ramona, Max, Tommy, Jackson and Pam. Jesse, however, becomes overstressed between Pam refusing to sleep, Ramona wanting him to fix her hair, Max and Jackson fighting over sharing a room and cooking Jesse food. This stress leads to Ramona ending up with wild hair when Jesse forgets to wash the perm solution out, burning Jackson's burgers, being shot in the face with fire retardant, hit in the head with the smoke alarm and Pam and Tommy drawing all over the kitchen counter. Jesse tells Stephanie and D.J. that he feels like he's lost his touch as a parent but they assure him that the loving uncle is still in there beneath all of the grumpiness. Jesse tenderheartedly helps Jackson and Max solve their issues with living together and Jesse, Stephanie and D.J. sing "(Let Me Be Your) Teddy Bear" to Pam and get her to sleep, similar to when Jesse, Danny and Joey sung it as a lullaby to baby Michelle.
Meanwhile, Fernando and Jimmy fix up the old Gibbler home as a surprise for Kimmy with Stephanie entering it for the first time. Stephanie and Kimmy, who previously argued over the house being haunted by a friendly ghost are met with flickering lights, Fernando's painting falling off the wall and the chandelier coming down onto the table, which scares Matt. Kimmy and Stephanie make up as she realizes that Kimmy was telling the truth about a ghost. However, Jimmy reveals that he was using a remote to cause the effects as D.J. wanted them to make up. Just as Stephanie gloats that she was right about there being no ghost, the electronics start to go off again but this time, Jimmy isn't the one causing it.
- Candace Cameron Bure as D.J. Tanner-Fuller
- Jodie Sweetin as Stephanie Tanner
- Andrea Barber as Kimmy Gibbler
- Soni Nicole Bringas as Ramona Gibbler
- Michael Campion as Jackson Fuller
- Elias Herger as Max Fuller
- Dashiell and Fox Messitt as Tommy Fuller Jr.
- Juan Pablo Di Pace as Fernando Guerrero
- Scott Weinger as Steve Hale
- Adam Hagenbuch as Jimmy Gibbler
| The image gallery for Uncle Jesse's Adventures in Babysitting may be viewed here.